Oleander Cellular location and expression of Na+, K+-ATPase α subunits affect the anti-proliferative activity of oleandrin￼. Posted on October 2012July 2022 by Carlos Torres 06 Oct Yang, P., Cartwright, C., Efuet, E., Hamilton, S. R., Wistuba, I. I., Menter, D., Addington, C., Shureqi, I. and Newman, R. A. (2012). Mol. Carcinog. doi: 10.1002/mc.21968. PMID: 23073998 Research Article: Cardiac glycosides exert anticancer effects by inducing immunogenic cell death. Digoxin and ouabain induce the efflux of cholesterol via liver X receptor signalling and the synthesis of ATP in cardiomyocytes.