An independent research group from Sapienza University in Italy has reported that oleandrin (key component in PBI-05204) significantly increased mouse survival and reduced brain tumor growth both directly on tumor cells and indirectly by promoting an antitumor brain microenvironment with a key protective role played by brain derived neurotrophic factor (BDNF).

 [Comment from Dr. Newman: These studies corroborated PBI’s findings on the important role of their drug for brain tumors and neurodegenerative disease]. The Journal of Neuroscience April, 2017; 37(14):3926-3939.

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Trade Article written by David Holley at Xconomy.

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