A manuscript describing the therapeutic effects of PBI-05204 against human pancreatic cancer implanted orthotopically (within the pancreas) in immunocompromised mice has been accepted for publication in Investigational New Drugs

 The article shows that the botanical drug PBI-05204 is effective in a dose dependent manner and superior to the standard-of-care approved drug known as gemcitabine. The title and authors are: PBI-05204, a supercritical CO₂ extract of Nerium oleander, inhibits growth of human pancreatic cancer via targeting the PI3K/mTOR pathway. Pan Y., Rhea, P.,Tan L, Lee H. J., Ravoori M., Addington C.,Gagea M., Kundra V, Kim S-J, Newman R.A., and Yang P. Read Article